Faculty

Kyle Bittinger, Ph.D.

Assistant Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition) at the Children's Hospital of Philadelphia

Department: Pediatrics

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

Children's Hospital of Philadelphia
Microbiome Center
Roberts Center for Pediatric Research
2716 South Street, 14th Floor
Philadelphia, PA 19146-2305

Office: 267-425-1641

Email:
bittingerk@chop.edu

Education:
B.S. (Chemistry)
University of Pittsburgh, 2001.
Ph.D. (Physical Chemistry)
Massachusetts Institute of Technology, 2008.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Wong SY, Estevinho MM, Heaney T, Marshall AA, Giselbrecht E, Daniel SG, Zhou C, Rosas-Villegas A, Jang KK, Yang H, Ko HM, Paulson JD, Ding Y, Bittinger K, Cho JH, Lewis JD, Ramanan D, Cadwell K: Goblet Cell Loss Linked to NOD2 and Secondary Resection in Crohn's Disease is Induced by Dysbiosis and Epithelial MyD88. Cell Mol Gastroenterol Hepatol May 2025 Notes: doi: 10.1016/j.jcmgh.2025.101533. Epub ahead of print.

Rotsaert C, Minnebo Y, Duysburgh C, Liu LS, Mahalak KK, Firman J, Mattei LM, Moustafa AM, Bittinger K, Hu W, Marzorati M, Michiels J, Van de Wiele T: Digestive parameters and gut microbiota load and composition along the in vivo piglet gastrointestinal tract. J Anim Sci Page: skaf107, May 2025.

Mulcrone PL, Narrowe A, Jones S, Hu W, Bittinger K, Moustafa AM, Liu L, Xiao W, Firrman J: Monitoring the Impact of Chlorinated Drinking Water on the Developing Gut Microbiota of Adolescent Mice Using Genetic Profiling. Int J Environ Stud 82(3): 1210, May 2025.

Hewlett KK, PeBenito A, Hecht AL, Tiffany C, Tanes C, Glover RC, Fawad JA, Friedman ES, Reynolds JC, Bittinger K, Lewis JD, Wu GD, Ahuja NK, Zackular JP: Dietary fiber modulates the window of susceptibility to Clostridioides difficile infection. Gastroenterology May 2025 Notes: doi: 10.1053/j.gastro.2025.04.027. Epub ahead of print.

Litichevskiy L, Considine M, Gill J, Shandar V, Cox TO, Descamps HC, Wright KM, Amses KR, Dohnalová L, Liou MJ, Tetlak M, Galindo-Fiallos MR, Wong AC, Lundgren P, Kim J, Uhr GT, Rahman RJ, Mason S, Merenstein C, Bushman FD, Raj A, Harding F, Chen Z, Prateek GV, Mullis M, Deighan AG, Robinson L, Tanes C, Bittinger K, Chakraborty M, Bhatt AS, Li H, Barnett I, Davenport ER, Broman KW, Levy M, Cohen RL, Botstein D, Freund A, Di Francesco A, Churchill GA, Li M, Thaiss CA: Gut metagenomes reveal interactions between dietary restriction, ageing and the microbiome in genetically diverse mice. Nat Microbiol 10(5): 1240, May 2025.

McGann C, Phyu R, Bittinger K, Mukhopadhyay S: Role of the Microbiome in Neonatal Infection: Pathogenesis and Implications for Management. Clin Perinatol 52(1): 147, Mar 2025.

Katona BW, Shukla A, Hu W, Nyul T, Dudzik C, Arvanitis A, Clay D, Dungan M, Weber M, Tu V, Hao F, Gan S, Chau L, Buchner AM, Falk GW, Jaffe DL, Ginsberg G, Palmer SN, Zhan X, Patterson AD, Bittinger K, Ni J: Microbiota and metabolite-based prediction tool for colonic polyposis with and without a known genetic driver. Gut Microbes 17(1): 2474141, Mar 2025.

Breton J, Tu V, Tanes C, Wilson N, Quinn R, Kachelries K, Friedman ES, Bittinger K, Baldassano RN, Compher C, Albenberg L: A pro-inflammatory diet is associated with growth and virulence of Escherichia coli in pediatric Crohn's disease. J Crohns Colitis 19(2): jjaf018, Feb 2025.

Thomas S, Bittinger K, Livornese LL Jr: Utilizing the biosimulator to analyze the environmental microbiome within the intensive care units of a hospital. Biotechniques 77(2): 66-75, Feb 2025.

Teles F, Martin L, Patel M, Hu W, Bittinger K, Kallan MJ, Chandrasekaran G, Cucchiara AJ, Giannobile WV, Stephens D, Kantarci A: Gingival Crevicular Fluid Biomarkers During Periodontitis Progression and After Periodontal Treatment. J Clin Periodontol 52(1): 40, Jan 2025.