Faculty

Parker C. Wilson, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine

Department: Pathology and Laboratory Medicine

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

713B Stellar-Chance Laboratories Building
Philadelphia, PA 19104

Office: 215 746 4321
Lab: 215 746 4321

Education:
BS (Biomedical Engineering with a Concentration in Computer Science)
Johns Hopkins University, 2005.
MD, PhD (Molecular and Cellular Biology and Pathobiology)
Medical University of South Carolina, 2013.

Links
Wilson lab GitHub
Wilson lab website

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Yuan M, Jin K, Yan H, Schroeder A, Luo C, Yao S, Dumoulin B, Levinsohn J, Luo T, Clemenceau JR, Jang I, Kim M, Liu Y, Deng M, Furth EE, Wilson P, Nayak A, Lubo I, Solis Soto LM, Wang L, Park JH, Susztak K, Hwang TH, Li M.: Smart spatial omics (S2-omics) optimizes region of interest selection to capture molecular heterogeneity in diverse tissues. Nat Cell Biol Dec 2025.

Gaut JP, Marsh JN, Chen L, Zhang F, Yu X, Wilson P, Liu TC, Swamidass SJ.: Superior transplant recipient outcome prediction and pathology assessment using rapid deep learning applied to procurement kidney biopsies. Sci Rep December 2025.

de Klerk JA, Slieker RC, Parker WC, Wu H, Muto Y, Postma RJ, 't Hart LM, Peerlings JHD, Herrewijnen F, Song H, Siebe Spijker H, Dumas SJ, Koning M, van der Pluijm LAK, Baelde HJ, Gerrits T, Rotmans JI, van Zonneveld AJ, van Solingen C, Humphreys BD, Bijkerk R: Cell Type-Specific Expression of Long Noncoding RNAs in Human Diabetic Kidneys Identifies TARID as a Key Regulator of Podocyte Function. Diabetes September 2025.

Cheng SY, Koppitch K, Guo J, Moy N, Simonian TL, Wilson PC, McMahon AP: Nfkb1 Removal from Proximal Tubule Cells Improves Renal Tubular Outcomes Following Ischemia Reperfusion Injury. Kidney360 June 2025 Notes: Analyzed scRNA-seq datasets of mice with kidney-specific Nfkb1 knockout to show changes in proximal tubule signaling pathways.

Khan S, Zaki A, Masood M, Khan A, Mohsin M, Verma A, Wilson PC, Ali S, Syed MA: Combating sepsis-induced acute lung injury: PARP1 inhibition mediates oxidative stress mitigation and miR-135a-5p/SMAD5/Nanog axis drives regeneration. Int Immunopharmacol January 2025.

Verma A, Wilson PC: Advances in Single-Cell Sequencing and Spatial Profiling of Kidney Disease. American Journal of Pathology January 2025.

Ihara K, Satake E, Wilson PC, Krolewski B, Kobayashi H, Md Dom ZI, Ricca J, Wilson J, Dreyfuss JM, Niewczas MA, Doria A, Nelson RG, Pezzolesi MG, Humphreys BD, Duffin K, Krolewski AS: Circulating proteins linked to apoptosis processes and fast development of end-stage kidney disease in diabetes. JCI Insight October 2024 Notes: Dr. Wilson conducted all of the single-cell analysis in this paper and demonstrated that the circulating proteins predictive of kidney disease progression likely originate from a specific population of injured proximal tubule cells.

Agraz JL, Agraz C, Chen AA, Rice C, Pozos RS, Aelterman S, Tan A, Viaene AN, Nasrallah MP, Sharma P, Grenko CM, Kurc T, Saltz J, Feldman MD, Akbari H, Shinohara RT, Bakas S, Wilson P: Optimized Whole-Slide-Image H&E Stain Normalization: A Step Towards Big Data Integration in Digital Pathology. IEEE Open J Eng Med Biol September 2024.

Agraz JL, Agraz C, Chen AA, Rice C, Pozos RS, Aelterman S, Tan A, Viaene AN, Nasrallah MP, Sharma P, Grenko CM, Kurc T, Saltz J, Feldman MD, Akbari H, Shinohara RT, Bakas S, Wilson P: Optimized Whole-Slide-Image H&E Stain Normalization: A Step Towards Big Data Integration in Digital Pathology. IEEE Open J Eng Med Biol September 2024.

Wallwork RS, Kotzin JJ, Cappelli LC, Mecoli C, Bingham CO 3rd, Wigley FM, Wilson PC, DiRenzo DD, Shah AA: Immune checkpoint inhibitor therapy in patients with cancer and pre-existing systemic sclerosis. Semin Arthritis Rheum May 2024 Notes: Contributed renal histology images of patients with systemic scleroderma.