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Faculty

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Jinbo Chen, Ph.D.

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Professor of Biostatistics in Biostatistics and Epidemiology
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Department: Biostatistics and Epidemiology
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46 Contact information
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University of Pennsylvania Perelman School of Medicine,
41 Department of Biostatistics, Epidemiology and Informatics
19 605 Blockley Hall
35 423 Guardian Drive
Philadelphia, PA 19104
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Email: jinboche@upenn.edu
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18 Publications
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13 Education:
21 9 B.S. 14 (Physics) c
3e Beijing Normal University, P.R. China, 1992.
 21 9 M.S. 1a (Biostatistics) c
3e University of Washington, Seattle, WA, 1999.
 21 a Ph.D. 1a (Biostatistics) c
3e University of Washington, Seattle, WA, 2002.
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Links
156 Search PubMed for articles
 87 CCEB > Statistical Genetics and Genomics
92 Center for Clinical Epidemiology and Biostatistics Faculty
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Description of Research Expertise

240 Dr. Jinbo Chen’s primary areas of research include the development of statistical methods for designing and analyzing two-phase epidemiologic studies, methodological and collaborative work in genetic association studies of complex diseases, and the development and evaluation of risk prediction models. Dr. Chen has published numerous methods papers on haplotype analysis using data from cohort, nested case-control, and matched case-control designs, methods on exploring gene-gene and gene-environment interactions, and efficient methods for screening SNP
1a8 genotypes. Her recent work has focused on design and analyses issues arising from studies of complex genetic and environmental effects on pregnancy-related and early-life disorders. Dr. Chen has been collaborating with researchers on dissecting genetic and environmental influences on the risk of biliary tract cancer, childhood leukemia, preterm birth, food allergy, and cardio-metabolic and cardiovascular diseases.
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Selected Publications

14c Chen J, Pee D, Ayyagari R, Graubard B, Schairer C, Byrne C, Benichou J, Gail, MH: Projecting absolute invasive breast cancer risk in white women with a model that includes mammographic density. Journal of the National Cancer Institute 98(17): 1215-1226, 2006.

 fe Wang L, Schnall J, Small A, Hubbard RA, Moore JH, Damrauer SM, Chen J: Case contamination in electronic health records based case-control studies. Biometrics 77(1): 67-77, Mar 2021.

 13a Parikh RB, Zhang Y, Kolla L, Chivers C, Courtright KR, Zhu J, Navathe AS, Chen J: Performance drift in a mortality prediction algorithm among patients with cancer during the SARS-CoV-2 pandemic. J Am Med Inform Assoc 30(2): 348-54, Jan 2023.

 fc Hasler JS, Ma Y, Wei YZ, Parikh R, Chen J: A Semiparametric Method for Risk Prediction Using Integrated Electronic Health Record Data. Ann. Appl. Stat 18(4): 3318-3337, Dec 2024.

 162 Dai G, Shao L, Chen J: Moving beyond population variable importance: concept, theory and applications of individual variable importance. Journal of the Royal Statistical Society Series B: Statistical Methodology Page: qkae11, Dec 2024 Notes: https://doi.org/10.1093/jrsssb/qkae115.

 13d Cao Y, Ma W, McCarthy A, Chen J: A constrained maximum likelihood approach to developing well-calibrated models for predicting binary outcomes. Lifetime Data Analysis 30: 624-648, May 2024 Notes: DOI https://doi.org/10.1007/s10985-024-09628-9.

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