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CVI Seminar Series
Weekly seminars hosted by the CVI
CVI Seminars for Spring 2026 will be held at 12:00 PM in Smilow TRC 11-146 unless otherwise specified. Please see weekly announcements for details. If you are unable to join us in-person, you can access the talk on Zoom via this link: https://pennmedicine.zoom.us/my/cviseminars
January 2026
January 12, 2026
Christine E. Seidman, MD
Harvard Medical School
“Direct Analyses of Hypertrophic Hearts: Insights into the Unknown”
*Physiology/CVI Joint Seminar, CRB Austrian Auditorium at 3:00pm*
January 14, 2026
Kiran Musunuru, MD, PhD, MPH, ML, MRA
Perelman School of Medicine
“Development and Deployment of Personalized Gene-editing Therapies”
January 21, 2026
Louise D. McCullough, MD, PhD
1f37McGovern Medical School at UTHealth
“Sex Differences in Stroke”
February 2026
February 4, 2026
Daniel Garry, MD, PhD
University of Minnesota
“Bioengineering Cardiovascular Organs”
February 11, 2026
Vineet Augustine, PhD
University of California, San Diego
“Neural Correlates Underlying Heart Disease”
February 18, 2026
William T. Pu, MD
Boston Children's Hospital
“iPSC-based Models of Heart Disease”
March 2026
March 4, 2026
Giovanni Ferrari, PhD
Columbia University
“Mechanobiology and Signaling Pathways Driving Mitral Valve Prolapse”
March 11, 2026
Christina Theodoris, MD, PhD
Gladstone Institutes for Cardiovascular Disease and Data Science and Biotechnology
“Transfer Learning to Enable Predictions for Network Biology”
March 18, 2026
Benoit Bruneau, PhD
UC San Francisco
“The Genomic Basis of Gene Regulation in Heart Development and Disease: Now in 3D!”
April 2026
April 1, 2026 (4pm Smilow 9-146)
Olujimi Ajijola, MD, PhD
UCLA
“The Dark Side of Adaptation: Neural Plasticity in Cardiovascular Disease”
April 8, 2026
Sharlene Day, MD
Perelman School of Medicine
“Hypertrophic Cardiomyopathy: Oh the Places We’ll Go”
April 15, 2026
Stavros G. Drakos, MD, PhD
CVRTI Muscle Biology Nora Eccles Harrison Cardiovascular Research and Training Institute
“Myocardial Recovery: Bedside to Bench and Back”
April 29, 2026
Kahlilia Morris-Blanco, PhD
Perelman School of Medicine
"From Local Cerebrovascular Injury to Global Brain Reprogramming in Aging"
May 2026
May 6, 2026
Philip S. Tsao, PhD
Stanford University
“Title TBD”
May 20, 2026
Federica Accornero, PhD
Brown University
"RNA-dependent Mechanisms of Heart Remodeling"
CVI Seminars for Fall 2025 will be held at 12:00 PM in Smilow TRC 11-146 unless otherwise specified. Please see weekly announcements for details. If you are unable to join us in-person, you can access the talk on Zoom via this link: https://pennmedicine.zoom.us/my/cviseminars
September 2025
September 10, 2025
Daniel Kelly, MD
University of Pennsylvania
“Locking and Unlocking Cardiac Maturation”
September 24, 2025
Alison Marsden, PhD
Stanford University
“Model Guided Treatment Planning in Congenital Heart Disease”
September 30, 2025
Robert Farese, MD
Memorial Sloan Kettering Cancer Center
“The Phase of Fat: Lipid Storage and Degradation in Cell Metabolism”
IDOM/CVI Joint Seminar, JMEC Law Auditorium
October 2025
October 8, 2025
Steven Marx, MD
Columbia University
“Unravelling the Mechanisms of Fight or Flight: How the Heart Responds to Adrenergic Signals”
October 15, 2025
Rajan Jain, MD
University of Pennsylvania
“3D Genome Organization in Cardiac Development and Disease”
October 22, 2025
Jeffery D. Molkentin, PhD
Cincinnati Children's Hospital
“The Latest from the Molkentin Laboratory”
November 2025
November 5, 2025
Mark Sellmyer, MD, PhD
University of Pennsylvania
“An Overview and Vignettes of Translational Research in the PET Center”
November 12, 2025
The Rodent Cardiovascular Phenotyping Core
University of Pennsylvania
“At the Core of Cardiac Function: Surgical and Echocardiographic Approaches in Rodent Cardiovascular Phenotyping”
December 2025
December 3, 2025
Han Zhu, MD
Stanford University
“Title TBD”
December 10, 2025
Benjamin Dibling, PhD
Penn Center for Innovation
“Lunch N Learn”
CVI Seminars for Spring 2025 will be held at 4:00 PM in Smilow TRC 11-146 unless otherwise specified. Please see weekly announcements for details. If you are unable to join us in-person, you can access the talk on Zoom via this link: https://pennmedicine.zoom.us/my/cviseminars
January 2025
January 8, 2025
Andrey Poleshko, PhD
University of Pennsylvania
“Organization of Lineage-Specific Transcriptional Enhancers in Specialized Chromatin Domains at the Nuclear Periphery”
January 15, 2025
Maria Basil, MD
Perelman School of Medicine
“The Role of the Respiratory Airways in Human Lung Development and Disease”
January 22, 2025
Eliot Peyster, MD
Perelman School of Medicine
"Translational Diagnostics with Computer Vision Technology: Using New Technology to Tackle Old Problems in Cardiovascular Medicine"
January 29, 2025
Courtney Griffin, PhD
Oklahoma Medical Research Foundation
“Manipulating Pathological Capillary Regression”
February 2025
February 5, 2025
Ali Javaheri, MD, PhD
Washington University School of Medicine
“Intermittent Fat-ing for Doxorubicin Cardiotoxicity: Not a Typo”
February 12, 2025
Bruce Gelb, MD
Icahn School of Medicine at Mount Sinai
“The Genetics of Congenital Heart Disease: Long, Dazed Journey into Clinic”
February 19, 2025
Katherine Gallagher, MD
University of Michigan
“Epigenetics in Cardiovascular Disease”
February 26, 2025
Noor Momin, PhD
University of Pennsylvania
“Immunotherapy for Cardiovascular Diseases”
March 2025
March 5, 2025
Gwen Randolph, PhD
Washington University School of Medicine
“Pathways that Govern Dissemination of Inflammatory Signals from the Intestine”
March 12, 2025 (Postponed)
Jeffery D. Molkentin, PhD
Cincinnati Children's Hospital Medical Center
"The Latest from the Molkentin Laboratory"
March 19, 2025
Stefania Nicoli, PhD
Yale School of Medicine
“Elevated Mitochondrial Activity During Embryogenesis Increases Adult Cerebrovascular Anomalies”
March 26, 2025
Santhi K. Ganesh, MD
University of Michigan
“Molecular and Genetic Progress in Understanding Arterial Dysplasia”
April 2025
April 2, 2025
Cat Makarewich, PhD
Cincinnati Children’s Hospital Medical Center
“Mining the Muscle Microproteome”
April 9, 2025
Junichi Sadoshima, PhD, MD
Rutgers New Jersey Medical School
“Perm1 Protects the Heart Against Ischemia”
April 16, 2025
Rong Tian, PhD, MD
University of Washington
“Metabolism Mechanisms in Pathological Cardiac Hypertrophy and Heart Failure”
April 23, 2025
Joseph Metzger, PhD
University of Minnesota
“Synthetic Bottlebrush Macromolecules Potently Prevent the Onset of Muscle Damage in Duchenne Muscular Dystrophy”
April 30, 2025
Timothy Hla, PhD
Harvard Medical School
“Synthetic Bottlebrush Macromolecules Potently Prevent the Onset of Muscle Damage in Duchenne Muscular Dystrophy”
May 2025
May 7, 2025 (Postponed)
Kahlilia Blanco, PhD
Perelman School of Medicine
May 14, 2025 (Postponed)
Kristy Red-Horse, PhD
Howard Hughes Medical Institute
May 21, 2025
David J. Glass MD
Regeneron Pharmaceuticals
“Effects of Aging on Skeletal Muscle”
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A
1ffdDale Abel, MD, PhD
University of California Los Angeles
Novel Mitochondrial Mechanisms for Cardiometabolic Disease
May 10, 2022
Ralf Adams, PhD
Westphalian Wilhelms-University
Organ-Specific and Functional Specialization of Vascular Cells
November 10, 2021
Elena Aikawa, MD, PhD
Harvard Medical School
New Insights into Cardiovascular Calcification
March 13, 2024
Pilar Alcaide, PhD, FAHA
Tufts University School of Medicine
Understanding T-Cell Immune Responses in Heart Failure
March 17, 2021
Inflammation at the Heart of Cardiac Remodeling
October 16, 2024
Zoltan Arany, MD, PhD
Perelman School of Medicine
New Players in Mitophagy
December 12, 2018
Update on Peripartum Cardiomyopathy: From Tiny Vessels to Gargantuan Proteins
January 17, 2024
Hossein Ardehali, MD, PhD
Northwestern University School of Medicine
Role of Iron in Cardiovascular Disease
October 18, 2023
Euan Ashley, MD
Stanford University
1 to 100,000 Single Cells to Populations in Cardiovascular Genomics
February 28, 2018
Vineet Augustine, PhD
Scripps Research
Peering Inside: Cardiac Interoceptive Neural Networks Governing Physiology and Behavior in Health and Disease
March 2, 2022
B
Johannes Backs, MD
Heidelberg University, Germany
HDAC4 in HFrEF and HFpEF
November 8, 2023
Robert Balaban, PhD
National Heart, Lung, and Blood Institute
The Mitochondria Reticulum of Muscle Cells
December 11, 2019
Joseph Baur, PhD
Perelman School of Medicine
NAD+ Metabolism in Health and Disease
May 17, 2023
Gerd Blobel, MD, PhD
Perelman School of Medicine
Genome and Epigenome Editing to Treat Hemoglobinopathies
March 14, 2018
Laurie Boyer, PhD
Massachusetts Institute of Technology
Programming and Reprogramming Cardiac Cell Fate
January 31, 2018
Paul Burridge, PhD
Northwestern University
Pharmacogenomic Prediction and Prevention of Chemotherapy-Induced Cardiotoxicity using hiPSC
January 16, 2019
Thomas Braun, MD, PhD
Max-Planck Institute
Reprogramming Cardiomyocytes for Heart Regeneration
March 6, 2024
Jonathan Brown, MD
Vanderbilt School of Medicine
DNA Base Editing in Progeria
February 9, 2022
Benoit Bruneau, PhD
Gladstone Institute of Cardiovascular Disease
Transcriptional Regulation of Heart Development and Congenital Heart Disease
Talk Link: https://mediasite.med.upenn.edu/mediasite/Play/142edd19adfe4641be5f89d059386d901d
December 16, 2020
C
Thomas Cappola, MD, ScM
Perelman School of Medicine
Crossing the Translational Divide in Heart Failure
November 20, 2019
Kathleen Caron, PhD
UNC-Chapel Hill
GPCR Regulation of Lymphatics in Health and Disease
February 13, 2019
GPCR Signaling in Cardiovascular Conditions
November 20, 2024
Stephen Chan, MD, PhD
University of Pittsburgh
Lysosomal Dysfunction Reprograms Endothelial Sterol Metabolism in Pulmonary Hypertension and Beyond
April 26, 2023
Neil Chi, MD, PhD
UCSD School of Medicine
A Change of Heart: Integrative Genetic Analyses of Cardiovascular Development and Disease
April 20, 2022
Mete Civelek, PhD
University of Virginia
Genetic Regulation of Vascular Smooth Muscle Cell Function
March 4, 2020
David Clapham, MD, PhD
Janelia Research Campus
A Serotonergic Axon-Cilium Synapse Drives Nuclear Signaling to Maintain Chromatin Accessibility
November 16, 2022
Kieran Clarke, PhD
University of Oxford
A Ketone Drink for Heart Failure?
February 27, 2019
Ondine Cleaver, PhD
UT Southwestern Medical Center
Building and Maintaining Biological Tubules
October 25, 2023
Frank Conlon, PhD
UNC School of Medicine
The Genetic and Molecular Basis of Cardiac Sex Differences
November 9, 2022
Kareen Coulombe, PhD
Brown University
Re-Engineering Myocardium for Heart Regeneration
January 29, 2020
Peter Crawford, MD, PhD
University of Minnesota
Following Ketone Carbon Through Macrophages, Landing in Hepatic Fibrogenesis
January 30, 2019
CVI COVID Dream Team Presentations
Perelman School of Medicine
Rajat Deo, MD, MTR
Marie Guerraty, MD, PhD
Siqi Gao, PhD/Mark Kahn, MD
Talk Link: https://upenn.box.com/s/upurxn45uc3r68nyrsvamj68d8xqd3ed
May 4, 2022
CVI Dream Team Initiative
Perelman School of Medicine
Mark Kahn, MD
John Welsh, PhD
Talk Link: https://upenn.box.com/s/ry9sr14ancwiimczt2aemmt67svhrvk4
May 12, 2021
Perelman School of Medicine
Jacob Brenner, MD, PhD
Vladimir Muzykantov, MD, PhD
January 19, 2022
CVI Special Seminar
Perelman School of Medicine
Cardiotropic Lipid Nanoparticles: Early Progress and Future Opportunities
Drew Weissman, MD, PhD
Kenneth Margulies, MD
Vladimir Muzykantov, MD, PhD
December 20, 2023
D
Scott Damrauer, MD
University of Pennsylvania
Aortic Aneurysms as Complex Traits: Insights from Human Genetics
September 18, 2024
Jennifer Davis, PhD
University of Washington
Regulated of Cardiac Fibroblast Fate and Fibrosis
November 11, 2020
Sharlene Day, MD
Perelman School of Medicine
Understanding Hypertrophic Cardiomyopathy: From Molecule to Patient
Talk Link: https://mediasite.med.upenn.edu/mediasite/Play/9a418ada639d4413865804ed4ec54fe11d
December 9, 2020
Vinicio de Jesus Perez, MD
Stanford University Medical Center
Inappropriate Angiogenesis in Pulmonary Arterial Hypertension: The Role of Pericytes
September 23, 2020
Arjun Deb, MD
UCLA Broad Stem Cell Research Center
How Hearts Regulate Scar Size
March 3, 2021
Stefanie Dimmeler, PhD
University of Frankfurt
The Critical Role of Cellular Communication in Cardiovascular Disease and Aging
September 29, 2021
Nicole Dubois, PhD
Icahn School of Medicine at Mount Sinai
2001
Cell type-specific requirement for RNA-binding protein DDX3X during cardiac development
November 30, 2022
E
Anne Eichmann, PhD
Yale School of Medicine
Heterogeneity of Endothelial Barrier Function Unraveled
February 24, 2021
Patrick Ellinor, MD, PhD
Massachusetts General Hospital
Atrial Fibrillation from Genetics to Mechanisms
March 6, 2019
John Elrod, PhD
Lewis Katz School of Medicine at Temple University
Mitochondrial Calcium Signaling in Cardiac Physiology and Disease
February 7, 2018
Jose Enríquez, PhD
Spanish National Center for Cardiovascular Research
Cardiomyocyte Mitochondrial Performance and Quality Control in Health and Disease
October 6, 2021
Slava Epelman, MD, PhD, FRCPC
University of Toronto
Cardiac Macrophages - Is the Sum Greater Than Its Parts?
May 19, 2021
Jonathan Epstein, MD
Perelman School of Medicine
mRNA-Based CAR T Therapy for Cardiac Fibrosis
February 16, 2022
Daria Esterhazy, PhD
University of Chicago
Immune Crosstalk through Shared Lymph Node Drainage in the Digestive System
October 19, 2022
F
Yi Fan, MD, PhD
Perelman School of Medicine
Vascular Niche in Cancer and Cardiovascular Diseases
February 22, 2023
Carlos Fernández-Hernando, PhD
Yale University School of Medicine
Macrophage Immunometabolic Responses in Atherosclerosis
October 5, 2022
Jason Fish, PhD
University Toronto
Decoding the Non-coding Regulatory Pathways of Vascular Inflammation
October 3, 2018
Glenn Fishman, MD
NYU Grossman School of Medicine
Cardiac Development: Serendipity in Discovery
October 23, 2024
Mark Fishman, MD
Massachusetts General Hospital
Genetic Architecture of Social Behavior in Zebrafish
May 9, 2018
Garret FitzGerald, MD
Perelman School of Medicine
Cardiovascular Hazard and NSAIDs
November 1, 2017
David Frank, MD, PhD
Children's Hospital of Philadelphia
Defining Mechanisms of Cardiopulmonary Cell Fate for Pediatric Pulmonary Hypertension Therapy
December 20, 2017
WNT Signaling Guides Spatiotemporal Allocation of Cardiopulmonary Progenitor Cells
September 28, 2022
Sarah Franklin, PhD
University of Utah School of Medicine
The Lysine Methyltransferase Smyd1 Regulates Growth and Metabolism in the Heart
September 25, 2019
G
Guillermo Garcia-Cardena, PhD
Brigham and Women’s Hospital, Boston
Novel Drivers of Endothelial Cell Dysfunction
April 10, 2019
Anna Gelzer DVM, PhD
School of Veterinary School of Medicine
Spontaneous Models of Arrhythmogenic, Cardiomyopathic, and Valvular Disease
February 12, 2020
Holger Gerhardt, PhD
Max-Delbrück Center for Molecular Medicine
Endothelial Dynamics in Vascular Patterning – News From the Junction
October 20, 2021
David Ginsburg, MD
University of Michigan Medical School
Genetics of Hemostasis: From Bedside to Bench and Back Again
November 13, 2024
Brian Glancy, PhD
NHLBI
The Muscle Mitochondrial Reticulum
May 2, 2018
Christopher Glass, MD, PhD
University of California San Diego
Decoding Macrophage Phenotypes in Health and Disease
September 12, 2023
David Glass, MD
Regeneron Pharmaceuticals, Inc. & Harvard Medical School
Molecular Mechanisms of Aging, Including in Skeletal Muscle
January 15, 2020
Ira Goldberg, MD
New York University Langone Health
Feeding the Heart with Fat
October 30, 2019
Marcus Goncalves, MD, PhD
Cornell University
Developing Precision Nutrition for Cancer
Talk Link: https://mediasite.med.upenn.edu/mediasite/Play/713fe65dcdf148308aa41e64d7088da21d
December, 2, 2020
Robert Gorman, MD
Perelman School of Medicine
Post-MI LV Remodeling: An Engineering Perspective with Implications for Regenerative Therapies
January 24, 2018
Daniel Greif, MD
Yale University School of Medicine
Vascular Mural Cells in Development and Disease
May 1, 2019
Courtney Griffin, PhD
University of Oklahoma Health Sciences Center
Exploiting Chromatin-Remodeling Complexes to Study Vascular Development and Maintenance
May 15, 2019
Chenghua Gu, DVM, PhD
Harvard Medical School
Neuro-Vascular Interactions in the Brain
December 6, 2023
Marie Guerraty, MD, PhD
Perelman School of Medicine
Molecular Insights in CMVD
February 8, 2023
Asa Gustafsson, PhD
Skaggs School of Pharmacy and Pharmaceutical Sciences
Novel Mechanisms of Mitochondrial Quality Control in the Heart
December 19, 2018
H
Saptarsi Haldar, MD
Amgen Inc.
Transcription Regulation in Cardiometabolic Physiology and Disease
March 16, 2022
Richard Harvey, PhD
Victor Chang Cardiac Research Institute
A Single Cell View of Cardiac Tissue Heterogeneity and Dynamics
September 22, 2021
Jorge Henao-Mejia, MD, PhD
Perelman School of Medicine
RNA Regulation of Inflammation
April 21, 2021
Denise Hilfiker-Kleiner, PhD
Hanover Medical School, University of Hanover
Update on Peripartum Cardiomyopathy
December 1, 2021
Travis Hinson, MD
The Jackson Laboratory
Decoding and Re-Writing the Broken Heart Genetic Code
March 29, 2023
Karen Hirschi, PhD
University of Virginia School of Medicine
Regulation of Endothelial Cell Specialization
April 19, 2023
Timothy Hla, PhD
Boston Children's Hospital
Novel Insights into Endothelial GPCR Regulation of Transcriptional Mechanisms of Angiogenesis and Organotypic Specialization
February 5, 2020
Benjamin Hogan, PhD
The University of Melbourne
New Molecular Regulators and Insights Into Lymphangiogenesis From the Zebrafish Embryo
November 3, 2021
Priscilla Hsue, MD
UCSF School of Medicine
HIV Infection, Inflammation and Cardiovascular Disease: 2018 Update
December 5, 2018
Guo Huang, PhD
University of California San Francisco
Understanding Organ Regeneration: An Adventure Following the Bat
December 11, 2024
I
1fdc
Erik Ingelsson MD, PhD, FAHA
Stanford University
Ten Years and Hundreds of Novel Cardiovascular Loci: What Now?
May 16, 2018
J
Iris Jaffe, MD, PhD
Tufts University School of Medicine
Vascular Mineralocorticoid Receptor: Evolutionary Mediator of Wound Healing Turned Harmful by our Modern Lifestyle
January 27, 2021
Isha Jain, PhD
Gladstone Institutes and UCSF
Turning the Oxygen and Vitamin Dials
February 10, 2021
Rajan Jain, MD
Perelman School of Medicine
Understanding How Genome Organization Regulates Cardiac Development and Disease
February 6, 2019
Siddhartha Jaiswal, MD, PhD
Stanford University
Clonal Hematopoiesis and Risk of Cardiovascular Diseases
Talk link: https://upenn.box.com/s/b27q31l8k186oafcchjwrug4jwomebwt
March 10, 2021
K
Mark Kahn, MD
Perelman School of Medicine
Valve Hemodynamics in Development and Disease
January 17, 2018
Using Mouse Models to Understand Disease Mechanism: Something Old and Something New
May 3, 2023
Ananth Karumanchi, MD
Cedars-Sinai Medical Center
Mechanisms of Preeclampsia: Implications for Cardiovascular Disease
November 1, 2023
David Kass, MD
John Hopkins University School of Medicine
How PKG Regulates Protein Quality Control
December 4, 2019
Recipe for making a HFpEF Heart
September 25, 2024
Daniel Kelly, MD
Perelman School of Medicine
Fuel Metabolic Checkpoints as Targets for Cardiovascular Disease
October 4, 2017
Mustafa Khokha, MD
Yale School of Medicine
Regional Specific Metabolism Dictates Cell Fate in the Embryo: Lessons from Patients with Congenital Heart Disease
January 25, 2023
Richard Kitsis, MD
Albert Einstein College of Medicine
Chemical and Structural Approaches to Manipulating Cell Death
November 7, 2018
Gou Young Koh, MD, PhD
KAIST, Seoul, Korea
Organ-specific Vasculatures: From Physiology to Pathophysiology
October 13, 2021
Maria Kontaridis, PhD
Masonic Medical Research Institute
Heart Disease: From Pediatric to Heart Failure
April 28, 2021
Marc Kraus, DVM
School of Veterinary School of Medicine
Spontaneous Models of Arrhythmogenic, Cardiomyopathic, and Valvular Disease
February 12, 2020
Calvin Kuo, MD, PhD
Stanford University School of Medicine
Molecular Regulation of the Blood-Brain Barrier
April 4, 2018
Genetic and Pharmacologic Manipulation of the Blood-Brain Barrier
April 24, 2024
Chulan Kwon, PhD, MS
John Hopkins Medicine
Cardiac Progenitor Development and Maturation
April 5, 2023
L
Jan Lammerding, PhD
Cornell University
Cardiac Laminopathies – New Insights and Potential Therapeutic Approaches
February 14, 2024
Kory Lavine, MD, PhD
Washington University School of Medicine in St. Louis
Leveraging Immune Cell Diversity in the Failing Heart
October 23, 2019
Nathan Lawson, PhD
University of Massachusetts Medical School
Implementing Conditional Genetics in Zebrafish to Study Vascular Development
September 20, 2023
Mitchell Lazar, MD, PhD
Perelman School of Medicine
Transcriptional Regulation of Metabolism
November 29, 2017
Control of Metabolism and Cardiac Function by Circadian REV-ERB Nuclear Receptors
September 8, 2021
Richard Lee, MD
Harvard University
Will We be Able to Regenerate Hearts?
April 14, 2021
Nicholas Leeper, MD
Stanford University School of Medicine
The Role of Efferocytosis in Cardiovascular Disease
September 19, 2018
Leslie Leinwand, PhD
Colorado University Denver School of Medicine
Myosin Myopathies: Pathogenesis and Therapeutic Potential
October 7, 2020
Guillaume Lettre, PhD
Montreal Heart Institute
Exploring the Role of Vascular Endothelial Cells in Coronary Artery Disease
December 15, 2021
Qin Li, PhD
Perelman School of Medicine
Immune Sensing of Self RNA in Inflammatory Diseases
April 10, 2024
Merry Lindsey, PhD
University of Mississippi
Cardiac Remodeling After Myocardial Infarction
October 2, 2019
Amanda Lund, PhD
NYU Grossman School of Medicine
Lymphatic Growth and Function in Health and Disease
January 31, 2024
M
Douglas Mann, MD
Washington University School of Medicine in St. Louis
The Role of Innate Immunity in Cardiac Injury and Repair
April 13, 2022
Andy Marks, MD
Columbia University
What Makes the Heart Pump: High Resolution Structure and Function of the Ryanodine Receptor
October 18, 2017
James Martin, MD, PhD
Baylor College of Medicine
Hippo Signaling in Heart Regeneration
January 10, 2018
Kathleen Martin, PhD
Yale School of Medicine
Epigenetic Regulation of Smooth Muscle Plasticity in Vascular Disease
April 27, 2022
Takashi Matsui, MD, PhD
John A. Burns School of Medicine
Ferroptosis in Cardiac Ischemia-Reperfusion Injury
April 17, 2024
Megan McCain, PhD
University of Southern California
Engineering "Heart on a Chip" Platforms for Cardiac Disease Modeling
March 13, 2019
Timothy McKinsey, PhD
University of Colorado Denver - Anschutz Medical Campus
Protein Acetylation in Heart Failure: The Epigenome and Beyond
April 11, 2018
Epigenetic Regulation of Cardiometabolic Disease: Expect the Unexpected
March 1, 2023
Elizabeth McNally, MD, PhD
Northwestern University
Genetic Determinants of Cardiac Function
January 13, 2021
Stryder Meadows, PhD
Tulane University
Molecular Mechanisms Driving Arteriovenous Malformations (AVMs) in Hereditary Hemorrhagic Telangiectasia (HHT)
March 27, 2024
Evangelos Michelakis, MD
Canadian Academy of Health Sciences
Cell Identity in the Cardiovascular System; From Snails to Ageing Research, to Vascular Disease and Heart Failure
January 24, 2024
Thomas Michel, MD, PhD
Harvard Medicine School
Chemogenetic Approaches to Modulate Cardiac and Neurovascular Oxidative Stress
May 10, 2023
Daniel Michele, PhD
University of Michigan
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Membrane Injury and Repair in Muscular Dystrophy and Dystrophic Cardiomyopathy
January 10, 2024
Karen Mohlke, PhD
Cornell University
Genetic Effects on Adipose and Liver Gene Expression at Cardiometabolic Trait Loci
January 26, 2022
Jeffery Molkentin, PhD
Cincinnati Children’s Hospital Medical Center
An Acute Immune Response Underlies the Benefit of Cardiac Adult Stem Cell Therapy
April 3, 2019
Kathryn Moore, PhD
New York University Langone Health
Impact of Cardiovascular Disease Beyond the Heart
January 11, 2023
Edward Morrisey, PhD
Perelman School of Medicine
Ensuring the Cardiovascular System Has Something to Work With: Building and Rebuilding the Lungs
March 20, 2019
Javid Moslehi, MD
UCSF School of Medicine
Cardio-Oncology: A Novel Platform for Cardiovascular Investigation
November 15, 2023
Deborah Muoio, PhD
Duke University Medical Center
Integrating Molecular Phenomics and Respiratory Fluxomics to Decipher the Metabolic Basis of Heart Failure
October 24, 2018
Elizabeth Murphy, PhD
NHLBI
Cell Death in Cardiac Ischemia and Reperfusion: The Role of Mitochondrial Ca2+ and the Mitochondrial Permeability Transition Pore
October 14, 2020
Charles Murry, MD, PhD
Keck School of Medicine of USC
Regenerating the Heart—Peeling an Onion?
October 9, 2024
Kiran Musunuru, MD, PhD
Perelman School of Medicine
Discovery and Therapeutic Genome Editing of Coronary Heart Disease Genes
December 6, 2017
Diagnosis, Prevention, and Treatment of Cardiovascular Diseases with Genome Editing
September 16, 2020
N
Matthias Nahrendorf, MD, PhD
Massachusetts General Hospital
Innate Immunity and Cardiovascular Health
October 16, 2019
Pradeep Natarajan, MD, MMSc
Harvard Medical School
Clonal Hematopoiesis of Indeterminate Potential and Coronary Artery Disease
December 13, 2023
Stefania Nicoli, PhD
Yale School of Medicine
RNA Mechanisms Governing Endothelial Cell Behaviors in Development and Homeostasis
January 22, 2020
O
Guillermo Oliver, PhD
Northwestern University
Lymphoangiocrine Factors in Cardiac Growth and Repair
October 30, 2024
Declan O'Regan, PhD
Institute of Clinical Sciences, Imperial College
Complex Traits in Cardiovascular Imaging
October 27, 2021
Michael Ostap, PhD
Perelman School of Medicine
Mechanochemistry of Cardiac Myosin: Force, Cardiomyopathy Mutations, and Drugs
February 17, 2021
Mark Oyama, DVM, MSCE
School of Veterinary School of Medicine
Spontaneous Models of Arrhythmogenic, Cardiomyopathic, and Valvular Disease
February 12, 2020
P
Timothy Padera, PhD
Massachusetts General Hospital and Harvard Medical School
The Lymphatic System in Health and Disease
September 27, 2023
Victoria Parikh, MD
Stanford University of California
Vascular Niche in Cancer and Cardiovascular Diseases
March 8, 2023
Kit Parker, PhD
Harvard University
Designing, Building, and Testing Muscular Pumps
February 20, 2019
Liming Pei, PhD
Perelman School of Medicine
Listen to your Heart
December 13, 2017
Single-Cell Genomics-Guided Mechanistic Understanding of Cardiovascular Disease
January 18, 2023
Mia Phillipson, PhD Uppsala
University
Fates and Functions of Perivascular Macrophages during Restoration of Blood Perfusion following Injury
March 30, 2022
Jorge Plutzky, MD
Harvard Medical School
Joint IDOM/CVI Seminar
May 22, 2019
Kenneth Poss, PhD
Duke University School of Medicine
Regulating Heart Regeneration
March 9, 2022
Michael Potente, MD
Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
Metabolic Regulation of Endothelial Growth State
October 9, 2019
Benjamin Prosser, PhD
Perelman School of Medicine
Cardiomyocyte Mechanobiology in Health and Heart Failure
September 26, 2018
William Pu, MD
Harvard Medical school & Boston Children's Hospital
From Engineered Tissue Models to Gene Therapy for Inherited Heart Disease
October 28, 2020
Q
Li Qian, PhD
University of North Carolina
Reprogramming Approach for Heart Repair
January 20, 2021
Altering Cell Fate for Heart Repair
October 4, 2023
R
Marlene Rabinovitch, MD
Stanford School of Medicine
Linking Genetic Perturbations to Vascular and Myeloid Cell Dysfunction to Find Therapies for Pulmonary Arterial Hypertension
April 3, 2024
Daniel Rader, MD
Perelman School of Medicine
New Biology in Cardiometabolic Traits Revealed Through Human Genetics
November 8, 2017
A Genome-First Approach to Cardiometabolic Disease
April 12, 2023
Kristy Red-Horse, PhD
Stanford University
Building and Rebuilding the Heart: Coronary Artery Development and Regeneration
January 23, 2019
Jalees Rehman, MD
The University of Illinois at Chicago
Endothelial Heterogeneity
February 15, 2023
Stacey Rentschler, MD, PhD
Washington University
Insights into Arrhythmia Mechanisms and Therapies from Cardiac Reprogramming
May 8, 2024
Marylyn Ritchie, PhD
Perelman School of Medicine
The Power of the Electronic Health Record for Precision Medicine
April 6, 2022
Howard Rockman, MD
Duke University School of Medicine
Biased G Protein-Coupled Receptor Signaling
March 27, 2019
Anthony Rosenzweig, MD
Harvard Medical School
Lnc’ing Exercise to Cardiovascular Benefits
February 2, 2022
Jared Rutter, PhD
University of Utah School of Medicine
Metabolism, Cellular Decisions and the Language That Unites Them
May 23, 2023
S
Michael Sacks, PhD
The University of Texas at Austin
Multi-Resolution Models of the Mitral Heart Valve: From Mechanobiology to Surgical Repair
October 31, 2018
Tamer Sallam, MD, PhD
UCLA
RNA Adventures in Cardiometabolic Disease
February 1, 2023
Vijay Sankaran, MD, PhD
Broad Institute of MIT and Harvard
Genetic Studies of Human Hematopoiesis
November 28, 2018
Amita Sehgal, PhD
Perelman School of Medicine
Circadian and Sleep Regulation of the Blood Brain Barrier
March 31, 2021
Jonathan Seidman, PhD
Harvard Medical School
The Genetics of Inherited Heart Disease: From Mutation to Mechanism to Therapy
February 3, 2021
Mark Sellmyer, MD, PhD
Perelman School of Medicine
Chemical Tools to Image and Control Gene/Cell Therapies
April 7, 2021
William Sessa, PhD
Pfizer
Regulation of Endothelial Cholesterol Homeostasis
March 23, 2022
Ajay Shah, MD, FMedSci
Tufts University School of Medicine
Understanding T-Cell Immune Responses in Heart Failure
November 17, 2021
Orian Shirihai, MD, PhD
UCLA
Social Life of Mitochondria Within the Cell
March 24, 2021
Arndt Siekmann, PhD
Perelman School of Medicine
Branching Morphogenesis: The Many Ways to Grow a Tree
November 18, 2020
Sydney Shaffer, MD, PhD
Perelman School of Medicine
Making Sense of Transcriptional Heterogeneity in Rare Cells
February 19, 2020
Shey-Shing Sheu, PhD, FAHA
Thomas Jefferson University
Defeating Heart Failure with Energy: Mechanisms of Cardiac Excitation-Contraction-Energetics Coupling
October 10, 2018
Raymond Soccio, MD, PhD
Perelman School of Medicine
Genetics of Gene Regulation by PPAR Nuclear Receptors in Cardiometabolic Disease
May 23, 2018
Bruce Spiegelman, PhD
Harvard Medical School
PGC1a/Irisin Pathway: Linking Exercise and Resistance to Neurodegeneration
October 2, 2024 (IDOM/CVI Joint Seminar)
Didier Stainier, PhD
Max Planck Institute for Heart and Lung Research
Biological Robustness: Genetic Compensation and Transcriptional Adaptation
February 26, 2020
Kristin Stanford, PhD
Ohio State University
New Mechanisms for BAT to Regulate the Heart
February 21, 2024
Matthew Steinhauser, MD
Brigham and Women’s Hospital, Division of Cardiovascular Medicine
White Adipose Plasticity and Systemic Insulin Resistance
November 13, 2019
Katalin Susztak, MD, PhD
Perelman School of Medicine
APOL1: The Balance Imposed by Infection, Selection, Kidney and Cardiovascular Disease
May 8, 2019
T
Ira Tabas, MD, PhD
Columbia University Irving Medical Center
Macrophage Metabolism in Atherosclerosis
September 3, 2019
Alan Tall, MD
Columbia University
Lipids, Hematopoiesis and Athero-Thrombosis
February 14, 2018
Jil Tardiff, MD, PhD
University of Arizona
Walking a Thin Line: Modulation of Cardiac Thin Filament Function in HCM and DCM
December 14, 2022
Rong Tian, MD, PhD
University of Washington
Is Metabolism a Driver in Pathological Remodeling of the Heart?
March 7, 2018
Sarah Tishkoff, PhD
Perelman School of Medicine
African Evolutionary Genomics: Implications for Evolution of Complex Traits and Diseases
December 18, 2024
Paul Titchenell, PhD
Perelman School of Medicine
Regulation of Muscle Growth and Metabolism by Insulin Signaling
October 11, 2023
U
V
Golnaz Vahedi, MSc, PhD
Perelman School of Medicine
Multiomics Single-Cell Analysis of Human Pancreatic Islets Reveals Novel Cellular States in Health and Type 1 Diabetes
May 5, 2021
Jolanda van der Velden, PhD
Netherlands Heart Institute Amsterdam
Cardiomyocyte Dysfunction in Hypertrophic Cardiomyopathy: Role of Sex and Gene Mutation
December 8, 2021
Benjamin Voight, PhD
Perelman School of Medicine
One Shot, One Opportunity: Making it Count with Computational Human Genomics
October 25, 2017
Tom Vondriska, PhD
UCLA
Epigenomics of Cardiovascular Disease
April 24, 2019
W
Douglas Wallace, PhD
Hospital of the University of Pennsylvania
A Mitochondrial Etiology of Complex Diseases
October 11, 2017
Kenneth Walsh, PhD
Boston University School of Medicine
Somatic Mutations, Clonal Hematopoiesis and Cardio-metabolic Risk
Jamuary 3, 2018
Yibin Wang, PhD
UCLA David Geffen School of Medicine
Common Pathway in Cardiometabolic Regulation: Signaling Beyond Bioenergetics
April 25, 2018
Brant Weinstein, PhD
National Institutes of Health
Fishing for New Insights into Vascular Biology and Epigenetics
November 6, 2024
Kathryn Wellen, PhD
Perelman School of Medicine
Acetyl-CoA Metabolism in Health and Disease
March 22, 2023
Hao Wu, PhD
Perelman School of Medicine
Decoding Human Ventricular Cardiomyocyte Specification and Maturation with Integrated Cell-Type Specific Epigenomic and Transcriptomic Analysis
October 17, 2018
Sean Wu, MD, PhD
Stanford School of Medicine
Application of AI/Machine Learning to Understand Cardiac Development
March 20, 2024
Gregory Wyant, PhD
Dana-Farber Cancer Institute and Harvard Medical School
Novel Mechanisms of Cardiac Ischemic Protection
October 12, 2022
Joshua Wythe, PhD
Baylor College of Medicine
Somatic KRAS Gain of Function in Sporadic Brain Arteriovenous Malformations
September 30, 2020
X
Yi Xing, PhD
Perelman School of Medicine
Long-Read Strategies to Study the Human Transcriptome
February 7, 2024
Y
Martin Young, PhD
The University of Alabama at Birmingham
Circadian Regulation of Cardiac Processes: Physiologic Importance and Pathologic Implications
Talk Link: https://mediasite.med.upenn.edu/mediasite/Play/3df03f6917d641db85da7f56234e0ae11d
November 4, 2020
Paul Yu, MD, PhD
Harvard Medical School
Translating Signaling and Genetics into Therapy for Pulmonary Vascular and Musculoskeletal Disease
November 2, 2022
Z
Payman Zamani, MD
Perelman Medical School
Thinking Beyond the Heart in Heart Failure with Preserved Ejection Fraction
May 1, 2024
Workshops
Hosted by Dr. Kiran Musunuru
Note: All workshops are RSVP REGISTRATION ONLY as seats are limited. Contact Emily Schuster (emily.schuster@pennmedicine.upenn.edu) for more information.
Tuesday, November 27, 2018 12pm, Smilow 11-146AB
CRISPR-Cas9 Genome Editing Bootcamp (Advanced Level)
Dr. Kiran Musunuru
Genome-editing tools, particularly CRISPR-Cas9, are transforming biomedical investigation. This practical, hands-on workshop, organized by the CVI Genetic and Epigenetic Origins of Disease (GEODe) Program, is intended for anybody interested in learning how to use CRISPR-Cas9-based technologies. The advanced-level workshop will follow a flipped-classroom, active-learning model. Participants will review an online video/slides before the meeting. In the workshop, participants will work in teams on virtual experiments in which base editing, epigenome editing, and other advanced concepts are explored (requiring participants to bring their own WiFi-capable laptops).
Tuesday, September 18, 2018 12pm, Smilow 11-146AB
CRISPR-Cas9 Genome Editing Bootcamp (Basic Level)
Dr. Kiran Musunuru
Genome-editing tools, particularly CRISPR-Cas9, are transforming biomedical investigation. This practical, hands-on workshop, organized by the CVI Genetic and Epigenetic Origins of Disease (GEODe) Program, is intended for anybody interested in learning how to use CRISPR-Cas9-based technologies. The basic-level workshop will follow a flipped-classroom, active-learning model. Participants will review an online video/slides before the meeting. In the workshop, participants will work in teams on virtual experiments in which knockout/knock-in mice and cell lines are generated (requiring participants to bring their own WiFi-capable laptops). Participants will learn online tools to design CRISPR-Cas9 reagents, common pitfalls to avoid, and interpreting data from genome-editing experiments.
Monday, May 14, 2018 12pm, Smilow 11-146AB
CRISPR-Cas9 Genome Editing Bootcamp (Advanced Level)
Dr. Kiran Musunuru
Genome-editing tools, particularly CRISPR-Cas9, are transforming biomedical investigation. This practical, hands-on workshop, organized by the CVI Genetic and Epigenetic Origins of Disease (GEODe) Program, is intended for anybody interested in learning how to use CRISPR-Cas9-based technologies. The advanced-level workshop will follow a flipped-classroom, active-learning model. Participants will review an online video/slides before the meeting. In the workshop, participants will work in teams on virtual experiments in which base editing, epigenome editing, and other advanced concepts are explored (requiring participants to bring their own WiFi-capable laptops).
Tuesday, January 23, 2018 12pm, Smilow 11-146AB
CRISPR-Cas9 Genome Editing Bootcamp (Basic Level)
Dr. Kiran Musunuru
Genome-editing tools, particularly CRISPR-Cas9, are transforming biomedical investigation. This practical, hands-on workshop, organized by the CVI Genetic and Epigenetic Origins of Disease (GEODe) Program, is intended for anybody interested in learning how to use CRISPR-Cas9-based technologies. The basic-level workshop will follow a flipped-classroom, active-learning model. Participants will review an online video/slides before the meeting. In the workshop, participants will work in teams on virtual experiments in which knockout/knock-in mice and cell lines are generated (requiring participants to bring their own WiFi-capable laptops). Participants will learn online tools to design CRISPR-Cas9 reagents, common pitfalls to avoid, and interpreting data from genome-editing experiments.
CV Grand Rounds
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